On May 7th, Canadian Federal Health Minister Agrouk announced at a press conference held in Ottawa on the 6th that Canadian scientists have completed the sequencing of the genes of three influenza A H1N1 influenza samples. This is the world’s The first complete sequencing of the new virus will lay the groundwork for vaccine development.
According to Hong Kong’s Ta Kung Pao and other media reports, Agrouk said that one of the virus samples came from Mexico and the other two came from Canada. Agrouk said that preliminary analysis showed that the three samples “have no significant differences at the genetic levelâ€. She said: "This is a complete sequence analysis of the H1N1 influenza virus gene and it is of great significance for us to understand this outbreak."
In addition, the World Health Organization responded to questions related to anti-viral drugs against H1N1 influenza A on the 6th. Influenza A viruses are sensitive to neuraminidase inhibitors, including Duffy and Zanamivir, and WHO reserves. Duffy can be used by about 5 million adults.
According to the World Health Organization, most patients infected with influenza A have experienced symptoms similar to common influenza, such as sore throats and coughing, and many patients are self-recovery without antiviral treatment.
Antiviral drugs can reduce these symptoms and shorten the course of the disease. In addition, antiviral drugs can effectively prevent exacerbations or death.
At present, there are mainly two types of anti-influenza virus drugs: one is the influenza virus neuraminidase inhibitors, including Tamiflu and Zanamivir; and the other is adamantanes, including amantadine and rimantadine.
The researchers found that the H1N1 influenza A virus is sensitive to neuraminidase inhibitors and resistant to adamantanes.
As the virus continues to mutate, it will become resistant to antiviral drugs. Therefore, WHO and its partners are closely monitoring the drug resistance of the virus.
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